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Year : 2020  |  Volume : 64  |  Issue : 6  |  Page : 112-116

Potential pharmacological agents for COVID-19

1 Professor, Department of Pharmacology, V. P. Chest Institute, University of Delhi, Delhi, India
2 Assistant Professor, Department of Internal Medicine, Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, Missouri, USA

Correspondence Address:
Anita Kotwani
Department of Pharmacology, V. P. Chest Institute, University of Delhi, Delhi - 110 007
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijph.IJPH_456_20

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A novel coronavirus disease 2019 (COVID-19) infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) first emerged in December 2019 in Wuhan, China, has become a global pandemic. Currently, the management of COVID-19 infection is mainly supportive. Several clinical trials worldwide are evaluating several drugs approved for other indications, as well as multiple investigational agents for the treatment and prevention of COVID-19. Here, we give a brief overview of pharmacological agents and other therapies which are under investigation as treatment options or adjunctive agents for patients infected with COVID-19 and for chemoprophylaxis for the prevention of COVID-19 infection. At the time of writing this commentary, there is no peer-reviewed published evidence from randomized clinical trials of any pharmacological agents improving outcomes in COVID-19 patients. However, it was reported that remdesivir an investigational antiviral agent hastens clinical recovery, but a study is yet to be published in peer-reviewed medical journal.

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