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SHORT COMMUNICATION
Year : 2012  |  Volume : 56  |  Issue : 4  |  Page : 297-300

Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal: Implications for population screening

Bhawna Bhutoria Jain1, Rabindra Nath Roy2, Sulekha Ghosh3, Tapan Ghosh4, Uma Banerjee5, Subodh Kumar Bhattacharya6
1 Assistant Professor, Department of Pathology, Burdwan Medical College, West Bengal, India
2 Associate Professor, Department of Community Medicine, Burdwan Medical College, West Bengal, India
3 Associate Professor, Department of Pathology, Burdwan Medical College, West Bengal, India
4 Demonstrator, Department of Pathology, Burdwan Medical College, West Bengal, India
5 Professor & Head, Department of Pathology, Burdwan Medical College, West Bengal, India
6 MSVP, Burdwan Medical College, West Bengal, India

Correspondence Address:
Bhawna Bhutoria Jain
Assistant Professor, Department of Pathology, Burdwan Medical College, Burdwan, West-Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-557X.106419

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Hemoglobinopathies are common genetic disorders of hemoglobin, which can be prevented by population screening and offering genetic counseling. In absence of population-based screening for hemoglobinopathies, the hospital-based diagnosis register provide idea about the extent of problem in the community. The present study was undertaken to find out the burden of hemoglobinopathies and spectrum of this disorders among the population who were screened in the hospital-based screening program. A record-basedanalysis of subjects who underwent screening for hemoglobinopathies in Burdwan Medical College and Hospital over a period of 3 years and 4 months revealed that overall 29.3% of subjects were positive for hemoglobinopathies. Beta thalassemia heterozygous was the most commonhemoglobinopathy in this region closely followed by hemoglobin E heterozygous. In view of high prevalence of hemoglobinopathies in this region, a routine premarital screening program is needed for identification and prevention of high-risk marriages.


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